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Membrane-associated aquaporin-1 facilitates osmotically driven water flux across the basolateral membrane of the thick ascending limb

The thick ascending limb of the loop of Henle (TAL) reabsorbs ∼30% of filtered NaCl but is impermeable to water. The observation that little water traverses the TAL indicates an absence of water channels at the apical membrane. Yet TAL cells swell when peritubular osmolality decreases indicating tha...

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Autors principals: Cabral, Pablo D., Herrera, Marcela
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468494/
https://ncbi.nlm.nih.gov/pubmed/22674028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00268.2012
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