Experimental and In Silico Modelling Analyses of the Gene Expression Pathway for Recombinant Antibody and By-Product Production in NS0 Cell Lines

Monoclonal antibodies are commercially important, high value biotherapeutic drugs used in the treatment of a variety of diseases. These complex molecules consist of two heavy chain and two light chain polypeptides covalently linked by disulphide bonds. They are usually expressed as recombinant prote...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mead, Emma J., Chiverton, Lesley M., Spurgeon, Sarah K., Martin, Elaine B., Montague, Gary A., Smales, C. Mark, von der Haar, Tobias
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468484/
https://ncbi.nlm.nih.gov/pubmed/23071804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047422
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