A mechanistic analysis of the role of microcalcifications in atherosclerotic plaque stability: potential implications for plaque rupture

The role of microcalcifications (μCalcs) in the biomechanics of vulnerable plaque rupture is examined. Our laboratory previously proposed (Ref. 44), using a very limited tissue sample, that μCalcs embedded in the fibrous cap proper could significantly increase cap instability. This study has been gr...

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Detalhes bibliográficos
Main Authors: Maldonado, Natalia, Kelly-Arnold, Adreanne, Vengrenyuk, Yuliya, Laudier, Damien, Fallon, John T., Virmani, Renu, Cardoso, Luis, Weinbaum, Sheldon
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Integrative Cardiovascular Physiology and Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468470/
https://ncbi.nlm.nih.gov/pubmed/22777419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00036.2012
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