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Synergistic Antitumor Effects of Endostar in Combination with Oxaliplatin via Inhibition of HIF and CXCR4 in the Colorectal Cell Line SW1116

Combination treatment with endostar, a novel modified endostatin, and cytotoxic chemotherapies showed a survival benefit in Chinese clinical trials. However, the exact mechanism for this synergism remains unclear. In this study, we report for the first time that the chemokine receptor CXCR4 and the...

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Dettagli Bibliografici
Autori principali: Jin, Fengyan, Ji, Huifan, Jia, Chunshu, Brockmeier, Ulf, Hermann, Dirk M., Metzen, Eric, Zhu, Yingqiao, Chi, Baorong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468460/
https://ncbi.nlm.nih.gov/pubmed/23071744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047161
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