The congenital bicuspid aortic valve can experience high-frequency unsteady shear stresses on its leaflet surface

The bicuspid aortic valve (BAV) is a common congenital malformation of the aortic valve (AV) affecting 1% to 2% of the population. The BAV is predisposed to early degenerative calcification of valve leaflets, and BAV patients constitute 50% of AV stenosis patients. Although evidence shows that genet...

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Главные авторы: Yap, Choon Hwai, Saikrishnan, Neelakantan, Tamilselvan, Gowthami, Vasilyev, Nikolai, Yoganathan, Ajit P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2012
Предметы:
Integrative Cardiovascular Physiology and Pathophysiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468455/
https://ncbi.nlm.nih.gov/pubmed/22821994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00829.2011
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