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Functional Assessment of Human Coding Mutations Affecting Skin Pigmentation Using Zebrafish
A major challenge in personalized medicine is the lack of a standard way to define the functional significance of the numerous nonsynonymous, single nucleotide coding variants that are present in each human individual. To begin to address this problem, we have used pigmentation as a model polygenic...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3468441/ https://ncbi.nlm.nih.gov/pubmed/23071798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047398 |
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