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Temporal regulation of HTLV-2 expression in infected cell lines and patients: evidence for distinct expression kinetics with nuclear accumulation of APH-2 mRNA

BACKGROUND: Human T-cell leukemia virus types 1 and 2 (HTLV-1 and HTLV-2) are delta retroviruses with similar genetic organization. Although both viruses immortalize T-cells in vitro, they exhibit distinct pathogenic potential in vivo. To search for possible differences in its expression strategy wi...

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Hlavní autoři: Bender, Cecilia, Rende, Francesca, Cotena, Alessia, Righi, Paola, Ronzi, Paola, Cavallari, Ilaria, Casoli, Claudio, Ciminale, Vincenzo, Bertazzoni, Umberto
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468393/
https://ncbi.nlm.nih.gov/pubmed/22973907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-74
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