In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells

OBJECTIVES: Aztreonam for inhalation solution (AZLI) was recently approved by the FDA for treating cystic fibrosis (CF) patients infected with Pseudomonas aeruginosa. Here we investigated the effect of aztreonam alone or in combination with tobramycin on P. aeruginosa biofilms grown on CF airway epi...

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Hlavní autoři: Yu, Qianru, Griffin, Edward F., Moreau-Marquis, Sophie, Schwartzman, Joseph D., Stanton, Bruce A., O'Toole, George A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2012
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468082/
https://ncbi.nlm.nih.gov/pubmed/22843834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dks296
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