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FacPad: Bayesian sparse factor modeling for the inference of pathways responsive to drug treatment
Motivation: It is well recognized that the effects of drugs are far beyond targeting individual proteins, but rather influencing the complex interactions among many relevant biological pathways. Genome-wide expression profiling before and after drug treatment has become a powerful approach for captu...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467747/ https://ncbi.nlm.nih.gov/pubmed/22923307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts502 |
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