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SimRare: a program to generate and analyze sequence-based data for association studies of quantitative and qualitative traits

Motivation: Currently, there is great interest in detecting complex trait rare variant associations using next-generation sequence data. On a monthly basis, new rare variant association methods are published. It is difficult to evaluate these methods because there is no standard to generate data and...

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Detalhes bibliográficos
Main Authors: Li, Biao, Wang, Gao, Leal, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467746/
https://ncbi.nlm.nih.gov/pubmed/22914216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts499
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