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Molecular mechanisms of genetic variation and transcriptional regulation of CYP2C19
Inherited variation in the function of the drug metabolizing enzyme CYP2C19 was first observed 40 years ago. The SNP variants which underpin loss of CYP2C19 function have been elucidated and extensively studied in healthy populations. However, there has been relatively meagre translation of this inf...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467616/ https://ncbi.nlm.nih.gov/pubmed/23087703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00206 |
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