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Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects.

The three major isoforms of human apolipoprotein E (apo-E2, -E3, and -E4) are coded for by three alleles (epsilon 2, epsilon 3, and epsilon 4) which have a common genetic locus. Previously, we demonstrated that E2, E3, and E4 differ in primary structure from one another at two substitution sites, si...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Rall, S C, Weisgraber, K H, Innerarity, T L, Mahley, R W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1982
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346743/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6289314/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.15.4696
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