Human Blood-Brain Barrier Endothelial Cells Derived from Pluripotent Stem Cells

The blood-brain barrier (BBB) plays an important role in brain health and is often compromised in disease. Moreover, as a result of its significant barrier properties, this endothelial interface restricts neurotherapeutic uptake. Thus, a renewable source of human BBB endothelium could prove enabling...

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Bibliographic Details
Main Authors: Lippmann, Ethan S., Azarin, Samira M., Kay, Jennifer E., Nessler, Randy A., Wilson, Hannah K., Al-Ahmad, Abraham, Palecek, Sean P., Shusta, Eric V.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467331/
https://ncbi.nlm.nih.gov/pubmed/22729031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2247
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