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Conditional Aurora A deficiency differentially affects early mouse embryo patterning
Aurora A is a mitotic kinase involved in centrosome maturation, spindle assembly and chromosome segregation during the cell division cycle. In mice, ablation of Aurora A results in mitotic arrest and pre-implantation lethality, preventing studies at later stages of development. Here we report the ef...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3467101/ https://ncbi.nlm.nih.gov/pubmed/22939930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.08.010 |
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