Expression of endogenous retroviruses is negatively regulated by the pluripotency marker Rex1/Zfp42

Rex1/Zfp42 is a Yy1-related zinc-finger protein whose expression is frequently used to identify pluripotent stem cells. We show that depletion of Rex1 levels notably affected self-renewal of mouse embryonic stem (ES) cells in clonal assays, in the absence of evident differences in expression of mark...

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Autori principali: Guallar, D., Pérez-Palacios, R., Climent, M., Martínez-Abadía, I., Larraga, A., Fernández-Juan, M., Vallejo, C., Muniesa, P., Schoorlemmer, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Gene Regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467079/
https://ncbi.nlm.nih.gov/pubmed/22844087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks686
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