Potent Antitumor Effects of Combination Therapy With IFNs and Monocytes in Mouse Models of Established Human Ovarian and Melanoma Tumors

Interferon-activated monocytes are known to exert cytocidal activity against tumor cells in vitro. Here, we have examined whether a combination of IFN-α2a and IFN-γ and human monocytes mediate significant antitumor effects against human ovarian and melanoma tumor xenografts in mouse models. OVCAR-3...

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Detalhes bibliográficos
Main Authors: Nakashima, Hideyuki, Miyake, Kotaro, Clark, Christopher R, Bekisz, Joseph, Finbloom, Joel, Husain, Syed R., Baron, Samuel, Puri, Raj K., Zoon, Kathryn C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3467013/
https://ncbi.nlm.nih.gov/pubmed/22159517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1152-x
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