Previously Transmitted HIV-1 Strains Are Preferentially Selected During Subsequent Sexual Transmissions

Background. A genetic bottleneck is known to exist for human immunodeficiency virus (HIV) at the point of sexual transmission. However, the nature of this bottleneck and its effect on viral diversity over time is unclear. Methods. Interhost and intrahost HIV diversity was analyzed in a stable popula...

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Autori principali: Redd, Andrew D., Collinson-Streng, Aleisha N., Chatziandreou, Nikolaos, Mullis, Caroline E., Laeyendecker, Oliver, Martens, Craig, Ricklefs, Stacy, Kiwanuka, Noah, Nyein, Phyu Hninn, Lutalo, Tom, Grabowski, Mary K., Kong, Xiangrong, Manucci, Jordyn, Sewankambo, Nelson, Wawer, Maria J., Gray, Ronald H., Porcella, Stephen F., Fauci, Anthony S., Sagar, Manish, Serwadda, David, Quinn, Thomas C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Major Articles and Brief Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466994/
https://ncbi.nlm.nih.gov/pubmed/22997233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis503
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