Ouabain Targets the Unfolded Protein Response for Selective Killing of HepG2 Cells During Glucose Deprivation

Ouabain is a cardiotonic steroid and specific inhibitor of the Na(+)/K(+)-ATPase. The relationship between ouabain treatment and the unfolded protein response (UPR) in cells is not precisely understood. Therefore, we studied the possible effects of ouabain on proliferation, apoptosis, and the UPR. H...

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Autors principals: Ozdemir, Tulay, Nar, Rukiye, Kilinc, Veli, Alacam, Hasan, Salis, Osman, Duzgun, Aynur, Gulten, Sedat, Bedir, Abdulkerim
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2012
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466918/
https://ncbi.nlm.nih.gov/pubmed/22757644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2011.1138
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