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Ouabain Targets the Unfolded Protein Response for Selective Killing of HepG2 Cells During Glucose Deprivation

Ouabain is a cardiotonic steroid and specific inhibitor of the Na(+)/K(+)-ATPase. The relationship between ouabain treatment and the unfolded protein response (UPR) in cells is not precisely understood. Therefore, we studied the possible effects of ouabain on proliferation, apoptosis, and the UPR. H...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ozdemir, Tulay, Nar, Rukiye, Kilinc, Veli, Alacam, Hasan, Salis, Osman, Duzgun, Aynur, Gulten, Sedat, Bedir, Abdulkerim
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466918/
https://ncbi.nlm.nih.gov/pubmed/22757644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2011.1138
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