Agonist-induced subsensitivity of adenylate cyclase coupled with a dopamine receptor in slices from rat corpus striatum.

Incubation, for 30 min, of striatal slices with 10 microM dopamine, 10 microM apomorphine, or 10 microM SKF 38393 decreased dopamine-stimulated adenylate cyclase activity by 50-60%. This loss in dopamine-stimulated enzyme activity appears to be mediated by a persistent occupancy of recognition sites...

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Hlavní autoři: Memo, M, Lovenberg, W, Hanbauer, I
Médium: Artigo
Jazyk:Inglês
Vydáno: 1982
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC346691/
https://ncbi.nlm.nih.gov/pubmed/6956874
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