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The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer

The combination of the mTOR inhibitor everolimus with the aromatase inhibitor exemestane was evaluated in the randomized Phase III BOLERO-2 trial. Research has indicated that aberrant signaling through the mTOR pathway is associated with resistance to endocrine therapies. The BOLERO-2 trial examined...

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Detalhes bibliográficos
Main Authors: Beaver, Julia A, Park, Ben H
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466807/
https://ncbi.nlm.nih.gov/pubmed/22764762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.12.49
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