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Induction of human beta-interferon synthesis with poly(rI . rC) in mouse cells transfected with cloned cDNA plasmids.

Human genomic DNA and plasmids carrying portions of the cDNA gene for human beta-interferon have been introduced into mouse Ltk- cells by cotransfection with a herpes simplex virus thymidine kinase (TK) gene. One plasmid contains 840 base pairs of human DNA complementary to pre-beta-interferon mRNA...

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Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Pitha, P M, Ciufo, D M, Kellum, M, Raj, N B, Reyes, G R, Hayward, G S
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1982
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Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC346666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6956863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.14.4337
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