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Paired Nanoinjection and Electrophysiology Assay to Screen for Bioactivity of Compounds using the Drosophila melanogaster Giant Fiber System

Screening compounds for in vivo activity can be used as a first step to identify candidates that may be developed into pharmacological agents(1,2). We developed a novel nanoinjection/electrophysiology assay that allows the detection of bioactive modulatory effects of compounds on the function of a n...

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Autors principals: Mejia, Monica, Heghinian, Mari D., Busch, Alexandra, Marí, Frank, Godenschwege, Tanja A.
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466648/
https://ncbi.nlm.nih.gov/pubmed/22525737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3597
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