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Paired Nanoinjection and Electrophysiology Assay to Screen for Bioactivity of Compounds using the Drosophila melanogaster Giant Fiber System
Screening compounds for in vivo activity can be used as a first step to identify candidates that may be developed into pharmacological agents(1,2). We developed a novel nanoinjection/electrophysiology assay that allows the detection of bioactive modulatory effects of compounds on the function of a n...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MyJove Corporation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3466648/ https://ncbi.nlm.nih.gov/pubmed/22525737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3597 |
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