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A Fluorescent Screening Assay for Identifying Modulators of GIRK Channels

G protein-gated inward rectifier K(+) (GIRK) channels function as cellular mediators of a wide range of hormones and neurotransmitters and are expressed in the brain, heart, skeletal muscle and endocrine tissue(1,2). GIRK channels become activated following the binding of ligands (neurotransmitters,...

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Autores principales: Vazquez, Maribel, Dunn, Charity A., Walsh, Kenneth B.
Formato: Artigo
Lenguaje:Inglês
Publicado: MyJove Corporation 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466633/
https://ncbi.nlm.nih.gov/pubmed/22706581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/3850
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