Inhibition of Hypoxia Inducible Factor-2 Transcription: Isolation of Active Modulators from Marine Sponges

Renal or kidney cancer accounts for about 3% of all cancer cases reported each year in the US. Molecular signatures that define the cancer, such as the loss of functional VHL, are found in both sporadic and familial cases of cancer. In clear cell renal cancer, the transcription factor HIF-2α has bee...

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Hlavní autoři: McKee, Tawnya C., Rabe, Daniel, Bokesch, Heidi R., Grkovic, Tanja, Whitson, Emily L., Diyabalanage, Thushara, Van Wyk, Albert W. W., Marcum, Stephanie R., Gardella, Roberta S., Gustafson, Kirk R., Linehan, W. Marston, McMahon, James B., Bottaro, Donald P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466586/
https://ncbi.nlm.nih.gov/pubmed/22928967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np300211x
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