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Reduced availability of endogenously synthesized methionine for S-adenosylmethionine formation in methionine-dependent cancer cells.

Methionine (Met) dependence--i.e., the inability of cultured cells to grow when Met is replaced by its immediate precursor homocysteine (Met-Hcy+ medium)--is a frequent component of the oncogenically transformed phenotype. Normal cells, on the other hand, grow in this medium. There have been reports...

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Bibliografski detalji
Glavni autori: Coalson, D W, Mecham, J O, Stern, P H, Hoffman, R M
Format: Artigo
Jezik:Inglês
Izdano: 1982
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC346647/
https://ncbi.nlm.nih.gov/pubmed/6289297
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