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The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds

Tissue-engineered constructs designed to treat large cartilage defects or osteoarthritic lesions may be exposed to significant mechanical loading as well as an inflammatory environment upon implantation in an injured or diseased joint. We hypothesized that a three-dimensionally (3D) woven poly(ε-cap...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Ousema, Paul H., Moutos, Franklin T., Estes, Bradley T., Caplan, Arnold I., Lennon, Donald P., Guilak, Farshid, Weinberg, J. Brice
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466362/
https://ncbi.nlm.nih.gov/pubmed/22999467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.08.045
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