The inhibition by interleukin 1 of MSC chondrogenesis and the development of biomechanical properties in biomimetic 3D woven PCL scaffolds

Tissue-engineered constructs designed to treat large cartilage defects or osteoarthritic lesions may be exposed to significant mechanical loading as well as an inflammatory environment upon implantation in an injured or diseased joint. We hypothesized that a three-dimensionally (3D) woven poly(ε-cap...

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Bibliografiske detaljer
Main Authors: Ousema, Paul H., Moutos, Franklin T., Estes, Bradley T., Caplan, Arnold I., Lennon, Donald P., Guilak, Farshid, Weinberg, J. Brice
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466362/
https://ncbi.nlm.nih.gov/pubmed/22999467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.08.045
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