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Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response

The DNA damage response (DDR) and DNA repair are critical for maintaining genomic stability and evading many human diseases [1, 2]. Recent findings indicate accumulation of SUN1, a nuclear envelope (NE) protein, is a significant pathogenic event in Emery-Dreifuss muscular dystrophy and Hutchinson-Gi...

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Bibliografiska uppgifter
Huvudupphovsmän: Lei, Kai, Zhu, Xiaoqiang, Xu, Rener, Xu, Tian, Zhuang, Yuan, Han, Min
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466333/
https://ncbi.nlm.nih.gov/pubmed/22863315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.06.043
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