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Genetic ablation of arginase 1 in macrophages and neutrophils enhances clearance of an arthritogenic alphavirus

Chikungunya virus (CHIKV) and Ross River virus (RRV) cause a debilitating, and often chronic, musculoskeletal inflammatory disease in humans. Macrophages constitute the major inflammatory infiltrates in musculoskeletal tissues during these infections. However, the precise macrophage effector functio...

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Autors principals: Stoermer, Kristina A., Burrack, Adam, Oko, Lauren, Montgomery, Stephanie A., Borst, Luke B., Gill, Ronald G., Morrison, Thomas E.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466331/
https://ncbi.nlm.nih.gov/pubmed/22972923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201240
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