Whole Genome Sequencing of Mutation Accumulation Lines Reveals a Low Mutation Rate in the Social Amoeba Dictyostelium discoideum

Spontaneous mutations play a central role in evolution. Despite their importance, mutation rates are some of the most elusive parameters to measure in evolutionary biology. The combination of mutation accumulation (MA) experiments and whole-genome sequencing now makes it possible to estimate mutatio...

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Detalhes bibliográficos
Main Authors: Saxer, Gerda, Havlak, Paul, Fox, Sara A., Quance, Michael A., Gupta, Sharu, Fofanov, Yuriy, Strassmann, Joan E., Queller, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466296/
https://ncbi.nlm.nih.gov/pubmed/23056439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046759
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