Impact of Cell Type and Epitope Tagging on Heterologous Expression of G Protein-Coupled Receptor: A Systematic Study on Angiotensin Type II Receptor

Despite heterologous expression of epitope-tagged GPCR is widely adopted for functional characterization, there is lacking of systematic analysis of the impact of expression host and epitope tag on GPCR expression. Angiotensin type II (AT2) receptor displays agonist-dependent and -independent activi...

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Bibliographic Details
Main Authors: Jiang, Lili, Teng, Gladys M. K., Chan, Elaine Y. M., Au, Shannon W. N., Wise, Helen, Lee, Susanna S. T., Cheung, Wing-Tai
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466278/
https://ncbi.nlm.nih.gov/pubmed/23056563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047016
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