Myb-Binding Protein 1A (MYBBP1A) Is Essential for Early Embryonic Development, Controls Cell Cycle and Mitosis, and Acts as a Tumor Suppressor

MYBBP1A is a predominantly nucleolar transcriptional regulator involved in rDNA synthesis and p53 activation via acetylation. However little further information is available as to its function. Here we report that MYBBP1A is developmentally essential in the mouse prior to blastocyst formation. In ce...

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Detalhes bibliográficos
Main Authors: Mori, Silvia, Bernardi, Rosa, Laurent, Audrey, Resnati, Massimo, Crippa, Ambra, Gabrieli, Arianna, Keough, Rebecca, Gonda, Thomas J., Blasi, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466261/
https://ncbi.nlm.nih.gov/pubmed/23056166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039723
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