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Simple Monitoring of Gene Targeting Efficiency in Human Somatic Cell Lines Using the PIGA Gene

Gene targeting in most of human somatic cell lines has been labor-intensive because of low homologous recombination efficiency. The development of an experimental system that permits a facile evaluation of gene targeting efficiency in human somatic cell lines is the first step towards the improvemen...

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Détails bibliographiques
Auteurs principaux: Karnan, Sivasundaram, Konishi, Yuko, Ota, Akinobu, Takahashi, Miyuki, Damdindorj, Lkhagvasuren, Hosokawa, Yoshitaka, Konishi, Hiroyuki
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466256/
https://ncbi.nlm.nih.gov/pubmed/23056640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047389
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