Probing the Mycobacterial Trehalome with Bioorthogonal Chemistry

[Image: see text] Mycobacteria, including the pathogen Mycobacterium tuberculosis, use the non-mammalian disaccharide trehalose as a precursor for essential cell-wall glycolipids and other metabolites. Here we describe a strategy for exploiting trehalose metabolic pathways to label glycolipids in my...

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Bibliographic Details
Main Authors: Swarts, Benjamin M., Holsclaw, Cynthia M., Jewett, John C., Alber, Marina, Fox, Douglas M., Siegrist, M. Sloan, Leary, Julie A., Kalscheuer, Rainer, Bertozzi, Carolyn R.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2012
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466019/
https://ncbi.nlm.nih.gov/pubmed/22978752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3062419
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