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Stereoselective Synthesis of Morpholines Via Copper-Promoted Oxyamination of Alkenes
[Image: see text] A new copper(II) 2-ethylhexanoate promoted addition of an alcohol and an amine across an alkene (oxyamination) is reported. The alcohol addition is intramolecular while coupling with the amine occurs intermolecularly. Several 2-aminomethyl morpholines were synthesized in good to ex...
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| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465956/ https://ncbi.nlm.nih.gov/pubmed/22894680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301984b |
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