Effect of Inhibition of Angiotensin-Converting Enzyme and/or Neutral Endopeptidase on Neuropathy in High-Fat-Fed C57Bl/6J Mice

We have demonstrated that treating diet-induced obese (DIO) mice with the vasopeptidase inhibitor ilepatril improved neural function. Vasopeptidase inhibitors block angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) activity. We propose that increased activity of ACE and NEP contrib...

Full description

Saved in:
Bibliographic Details
Main Authors: Coppey, Lawrence, Lu, Bao, Gerard, Craig, Yorek, Mark A.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465928/
https://ncbi.nlm.nih.gov/pubmed/23056927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/326806
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items