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Donor Satellite Cell Engraftment is Significantly Augmented When the Host Niche is Preserved and Endogenous Satellite Cells are Incapacitated

Stem cell transplantation is already in clinical practice for certain genetic diseases and is a promising therapy for dystrophic muscle. We used the mdx mouse model of Duchenne muscular dystrophy to investigate the effect of the host satellite cell niche on the contribution of donor muscle stem cell...

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Detalhes bibliográficos
Main Authors: Boldrin, Luisa, Neal, Alice, Zammit, Peter S, Muntoni, Francesco, Morgan, Jennifer E
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465801/
https://ncbi.nlm.nih.gov/pubmed/22730231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1158
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