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The extracellular matrix proteoglycan perlecan facilitates transmembrane semaphorin-mediated repulsive guidance
The Drosophila transmembrane semaphorin-1a (Sema-1a) is a repulsive guidance cue that uses the Plexin A (PlexA) receptor during neural development. Sema-1a is required in axons to facilitate motor axon defasciculation at guidance choice points. We found that mutations in the trol gene strongly suppr...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465742/ https://ncbi.nlm.nih.gov/pubmed/23028146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.193136.112 |
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