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Regulation of the Hippo–YAP pathway by protease-activated receptors (PARs)
The Hippo signaling pathway plays a crucial role in tissue growth and tumorigenesis. Core components of the Hippo pathway include the MST1/2 and Lats1/2 kinases. Acting downstream from the Hippo pathway are the YAP/TAZ transcription coactivators, which are inhibited through phosphorylation by Lats....
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465735/ https://ncbi.nlm.nih.gov/pubmed/22972936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.197582.112 |
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