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Efficient calculation of molecular configurational entropies using an information theoretic approximation

Accurate computation of free energy changes upon molecular binding remains a challenging problem, and changes in configurational entropy are especially difficult due both to the potentially large numbers of local minima, anharmonicity, and high-order coupling among degrees of freedom. Here we propos...

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Autors principals: King, Bracken M., Silver, Nathaniel W., Tidor, Bruce
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465721/
https://ncbi.nlm.nih.gov/pubmed/22229789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp2068123
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