MKK4 Suppresses Metastatic Colonization by Multiple Highly Metastatic Prostate Cancer Cell Lines Through a Transient Impairment in Cell Cycle Progression

Metastatic dissemination in prostate cancer is often early, however not all cancer cells form clinical metastases. Map kinase kinase 4 (MKK4) suppresses metastasis in a preclinical prostate cancer model. We hypothesize that MKK4 will specifically inhibit metastatic colonization through impaired prol...

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Bibliografische gegevens
Hoofdauteurs: Szmulewitz, Russell Z, Clark, Robert, Lotan, Tamara, Otto, Kristen, Veneris, Jennifer Taylor, Macleod, Kay, Rinker-Schaeffer, Carrie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465713/
https://ncbi.nlm.nih.gov/pubmed/21351092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.26005
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