DOR activation inhibits anoxic/ischemic Na(+) influx through Na(+) channels via PKC mechanisms in the cortex

Activation of delta-opioid receptors (DOR) is neuroprotective against hypoxic/ischemic injury in the cortex, which is at least partially related to its action against hypoxic/ischemic disruption of ionic homeostasis that triggers neuronal injury. Na(+) influx through TTX-sensitive voltage-gated Na(+...

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Main Authors: Chao, Dongman, He, Xiaozhou, Yang, Yilin, Bazzy-Asaad, Alia, Lazarus, Lawrence H., Balboni, Gianfranco, Kim, Dong H., Xia, Ying
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465681/
https://ncbi.nlm.nih.gov/pubmed/22609332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.05.006
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