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Phosphate disruption and metal toxicity in Saccharomyces cerevisiae: Effects of RAD23 and the histone chaperone HPC2

In cells, there exists a delicate balance between accumulation of charged metal cations and abundant anionic complexes such as phosphate. When phosphate metabolism is disrupted, cell-wide spread disturbances in metal homeostasis may ensue. The best example is a yeast pho80 mutant that hyperaccumulat...

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Detalhes bibliográficos
Main Authors: Rosenfeld, Leah, Culotta, Valeria C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465668/
https://ncbi.nlm.nih.gov/pubmed/22281500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.01.047
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