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Nod1, but not the ASC inflammasome, contributes to induction of IL-1β secretion in human trophoblasts after sensing of Chlamydia trachomatis
Chlamydia trachomatis (Ct) is an obligate intracellular bacterial pathogen. Previously, we showed that infection of human trophoblast cells by Ct triggers the secretion of the pro-inflammatory cytokine, IL-1β. The aim of this study was to understand the innate immune pathways involved in trophoblast...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465624/ https://ncbi.nlm.nih.gov/pubmed/22763410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.63 |
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