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The Par Complex and Integrins Direct Asymmetric Cell Division in Adult Intestinal Stem Cells

The adult Drosophila midgut is maintained by intestinal stem cells (ISCs) that generate both self-renewing and differentiating daughter cells. How this asymmetry is generated is currently unclear. Here, we demonstrate that asymmetric ISC division is established by a unique combination of extracellul...

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Bibliografiska uppgifter
Huvudupphovsmän: Goulas, Spyros, Conder, Ryan, Knoblich, Juergen A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465556/
https://ncbi.nlm.nih.gov/pubmed/23040479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.06.017
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