Esrrb Is a Pivotal Target of the Gsk3/Tcf3 Axis Regulating Embryonic Stem Cell Self-Renewal

Inhibition of glycogen synthase kinase-3 (Gsk3) supports mouse embryonic stem cells (ESCs) by modulating Tcf3, but the critical targets downstream of Tcf3 are unclear. We analyzed the intersection between genome localization and transcriptome data sets to identify genes repressed by Tcf3. Among thes...

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Hlavní autoři: Martello, Graziano, Sugimoto, Toshimi, Diamanti, Evangelia, Joshi, Anagha, Hannah, Rebecca, Ohtsuka, Satoshi, Göttgens, Berthold, Niwa, Hitoshi, Smith, Austin
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465555/
https://ncbi.nlm.nih.gov/pubmed/23040478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2012.06.008
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