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Superior analgesic effect of H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), a multifunctional opioid peptide, compared to morphine in a rat model of neuropathic pain
H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), is a synthetic tetrapeptide with extraordinary selectivity for the mu-opioid receptor and is an extremely potent analgesic. [Dmt(1)]DALDA is unusual in the way that the greater part of its analgesic potency appears to be produced by its actions in the spina...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465489/ https://ncbi.nlm.nih.gov/pubmed/22834682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12003 |
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