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Superior analgesic effect of H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), a multifunctional opioid peptide, compared to morphine in a rat model of neuropathic pain

H-Dmt-D-Arg-Phe-Lys-NH(2) ([Dmt(1)]DALDA), is a synthetic tetrapeptide with extraordinary selectivity for the mu-opioid receptor and is an extremely potent analgesic. [Dmt(1)]DALDA is unusual in the way that the greater part of its analgesic potency appears to be produced by its actions in the spina...

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Detaylı Bibliyografya
Asıl Yazarlar: Shimoyama, Megumi, Schiller, Peter W., Shimoyama, Naohito, Toyama, Satoshi, Szeto, Hazel H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465489/
https://ncbi.nlm.nih.gov/pubmed/22834682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12003
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