Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

Detection of microbial products by host inflammasomes is critical for innate immune surveillance. Inflammasomes activate the CASPASE-1 (CASP1) protease, which processes the cytokines interleukin(IL)-1β and -18, and initiates a lytic host cell death called pyroptosis(1). To identify novel CASP1 funct...

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Detalhes bibliográficos
Main Authors: von Moltke, Jakob, Trinidad, Norver J., Moayeri, Mahtab, Kintzer, Alexander F., Wang, Samantha B., van Rooijen, Nico, Brown, Charles R., Krantz, Bryan A., Leppla, Stephen H., Gronert, Karsten, Vance, Russell E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465483/
https://ncbi.nlm.nih.gov/pubmed/22902502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11351
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