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Pregnancy imprints regulatory memory that sustains anergy to fetal antigen
Pregnancy is an intricately orchestrated process where immune effector cells with fetal specificity are selectively silenced. This requires the sustained expansion of immune suppressive maternal Foxp3(+) regulatory T cells (Tregs), because even transient partial ablation triggers fetal-specific effe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3465465/ https://ncbi.nlm.nih.gov/pubmed/23023128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11462 |
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