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Pregnancy imprints regulatory memory that sustains anergy to fetal antigen

Pregnancy is an intricately orchestrated process where immune effector cells with fetal specificity are selectively silenced. This requires the sustained expansion of immune suppressive maternal Foxp3(+) regulatory T cells (Tregs), because even transient partial ablation triggers fetal-specific effe...

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Main Authors: Rowe, Jared H., Ertelt, James M., Xin, Lijun, Way, Sing Sing
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465465/
https://ncbi.nlm.nih.gov/pubmed/23023128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11462
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