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Degradation of the antiviral component ARGONAUTE1 by the autophagy pathway

Posttranscriptional gene silencing (PTGS) mediated by siRNAs is an evolutionarily conserved antiviral defense mechanism in higher plants and invertebrates. In this mechanism, viral-derived siRNAs are incorporated into the RNA-induced silencing complex (RISC) to guide degradation of the corresponding...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Derrien, Benoît, Baumberger, Nicolas, Schepetilnikov, Mikhail, Viotti, Corrado, De Cillia, Julia, Ziegler-Graff, Véronique, Isono, Erika, Schumacher, Karin, Genschik, Pascal
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3465452/
https://ncbi.nlm.nih.gov/pubmed/23019378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209487109
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